Integrated Analysis of Differentially Expressed miRNAs and mRNAs in Goat Skin Fibroblast Cells in Response to Orf Virus Infection Reveals That cfa-let-7a Regulates Thrombospondin 1 Expression

Integrated Analysis of Differentially Expressed miRNAs and mRNAs in Goat Skin Fibroblast Cells in Response to Orf Virus Infection Reveals That cfa-let-7a Regulates Thrombospondin 1 Expression

Orf is a zoonotic disease that has caused huge economic losses globally. Systematical analysis of dysregulated cellular micro RNAs (miRNAs) in response to Orf virus (ORFV) infection has not been reported. In the current study, miRNA sequencing and RNA sequencing (RNA-seq) were performed in goat skin...

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Bibliographic Details
Main Authors: Feng Pang, Xinying Wang, Zhen Chen, Zhenxing Zhang, Mengmeng Zhang, Chengqiang Wang, Xiaohong Yang, Qi An, Li Du, Fengyang Wang
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Viruses
Subjects:
orf virus
gsf cells
interaction between virus and host cells
mrnas
mirnas
cfa-let-7a
thbs1
Online Access:https://www.mdpi.com/1999-4915/12/1/118

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https://www.mdpi.com/1999-4915/12/1/118

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