The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects

The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects

SWR-C and its substrate the histone variant Htz1 are considered important for genome maintenance. Here the authors reveal that SWR-C/Htz1 plays a critical role during replication stress caused by absence of the replication fork progression proteins Mrc1/Tof1/Csm3.

Bibliographic Details
Main Authors: Anjana Srivatsan, Bin-Zhong Li, Barnabas Szakal, Dana Branzei, Christopher D. Putnam, Richard D. Kolodner
Format: Article
Language:English
Published: Nature Portfolio 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06131-2

Internet

https://doi.org/10.1038/s41467-018-06131-2

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