Mitochondria-derived superoxide links to tourniquet-induced apoptosis in mouse skeletal muscle.

Our previous study has reported that superoxide mediates ischemia-reperfusion (IR)-induced necrosis in mouse skeletal muscle. However, it remains poorly understood whether IR induces apoptosis and what factors are involved in IR-induced apoptosis in skeletal muscle. Using a murine model of tournique...

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Bibliographic Details
Main Authors: Thai P Tran, Huiyin Tu, Jinxu Liu, Robert L Muelleman, Yu-Long Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422247?pdf=render