ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy

ROR1 and ROR2 in Human Malignancies: Potentials for Targeted Therapy

Targeted therapies require cellular protein expression that meets specific requirements that will maximize effectiveness, minimize off-target toxicities, and provide an opportunity for a therapeutic effect. The receptor tyrosine kinase-like orphan receptors (ROR) are possible targets for therapy t...

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Bibliographic Details
Main Authors: Guilly eRebagay, Su eYan, Cheng eLiu, Nai-Kong eCheung
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Oncology
Subjects:
Immunotherapy
receptor tyrosine kinase orphan receptors
ROR1/ROR2
Solid tumor
Wnt/Beta-Catenin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00034/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00034/full

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