Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes

Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes

Inwardly rectifying potassium (Kir) 4.1 channels in astrocytes regulate neuronal excitability by mediating spatial potassium buffering. Although dysfunction of astrocytic Kir4.1 channels is implicated in the development of epileptic seizures, the functional mechanisms of Kir4.1 channels in modulatin...

詳細記述

書誌詳細
主要な著者: Masato Kinboshi, Takahiro Mukai, Yuki Nagao, Yusuke Matsuba, Yoshimi Tsuji, Shiho Tanaka, Kentaro Tokudome, Saki Shimizu, Hidefumi Ito, Akio Ikeda, Atsushi Inanobe, Yoshihisa Kurachi, Seiji Inoue, Yukihiro Ohno
フォーマット: 論文
言語:English
出版事項: Frontiers Media S.A. 2017-12-01
シリーズ:Frontiers in Molecular Neuroscience
主題:
astrocytes
Kir4.1 channels
BDNF
epilepsy
antidepressants
オンライン･アクセス:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00408/full

インターネット

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00408/full

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