Phospho-Tyr705 of STAT3 is a therapeutic target for sepsis through regulating inflammation and coagulation

Phospho-Tyr705 of STAT3 is a therapeutic target for sepsis through regulating inflammation and coagulation

Abstract Background Sepsis is an infection-induced aggressive and life-threatening organ dysfunction with high morbidity and mortality worldwide. Infection-associated inflammation and coagulation promote the progression of adverse outcomes in sepsis. Here, we report that phospho-Tyr705 of STAT3 (pY-...

Full description

Bibliographic Details
Main Authors: Shunyao Xu, Xiaojun Pan, Lingjie Mao, Hao Pan, Wenwei Xu, Yufeng Hu, Xueshu Yu, Zhiqiang Chen, Songzan Qian, Yincai Ye, Yueyue Huang, Jingye Pan
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Cell Communication and Signaling
Subjects:
Sepsis
STAT3
Inflammation
Coagulation
Online Access:http://link.springer.com/article/10.1186/s12964-020-00603-z

Internet

http://link.springer.com/article/10.1186/s12964-020-00603-z

Similar Items