Preparation, Optimization, and In-Vitro Evaluation of Brusatol- and Docetaxel-Loaded Nanoparticles for the Treatment of Prostate Cancer

Preparation, Optimization, and In-Vitro Evaluation of Brusatol- and Docetaxel-Loaded Nanoparticles for the Treatment of Prostate Cancer

Challenges to docetaxel use in prostate cancer treatment include several resistance mechanisms as well as toxicity. To overcome these challenges and to improve the therapeutic efficacy in heterogeneous prostate cancer, the use of multiple agents that can destroy different subpopulations of the tumor...

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Bibliographic Details
Main Authors: Tayo Alex Adekiya, Madison Moore, Michael Thomas, Gabriel Lake, Tamaro Hudson, Simeon K. Adesina
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Pharmaceutics
Subjects:
prostate cancer
docetaxel
brusatol
nanoparticles
cell cycle
caspase activity
Online Access:https://www.mdpi.com/1999-4923/16/1/114

Internet

https://www.mdpi.com/1999-4923/16/1/114

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