4-tert-butylphenol triggers common carp hepatocytes ferroptosis via oxidative stress, iron overload, SLC7A11/GSH/GPX4 axis, and ATF4/HSPA5/GPX4 axis

4-tert-butylphenol triggers common carp hepatocytes ferroptosis via oxidative stress, iron overload, SLC7A11/GSH/GPX4 axis, and ATF4/HSPA5/GPX4 axis

4-tert-butylphenol (4-tBP) is a toxic environmental pollutant with moderate bioaccumulation, environmental persistence, and long-term toxicity. Its toxicity to aquatic organisms has become an issue of concern. However, the molecular mechanism of 4-tBP toxicity to aquatic organisms remained unclear....

Full description

Bibliographic Details
Main Authors: Jiawen Cui, Qin Zhou, Meijin Yu, Yuhao Liu, Xiaohua Teng, Xianhong Gu
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Environmental pollutant
4-tert-butylphenol
Ferrostatin-1
ROS
Iron homeostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322007849

Internet

http://www.sciencedirect.com/science/article/pii/S0147651322007849

Similar Items