Susceptibility of human melanoma cells to autologous natural killer (NK) cell killing: HLA-related effector mechanisms and role of unlicensed NK cells.

Susceptibility of human melanoma cells to autologous natural killer (NK) cell killing: HLA-related effector mechanisms and role of unlicensed NK cells.

BACKGROUND: Despite Natural Killer (NK) cells were originally defined as effectors of spontaneous cytotoxicity against tumors, extremely limited information is so far available in humans on their capability of killing cancer cells in an autologous setting. METHODOLOGY/PRINCIPAL FINDINGS: We have est...

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Bibliographic Details
Main Authors: Paolo Carrega, Gaetana Pezzino, Paola Queirolo, Irene Bonaccorsi, Michela Falco, Giuseppe Vita, Daniela Pende, Aldo Misefari, Alessandro Moretta, Maria Cristina Mingari, Lorenzo Moretta, Guido Ferlazzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2780723?pdf=render

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http://europepmc.org/articles/PMC2780723?pdf=render

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