Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells

Chromosome conformation capture (3C) techniques are crucial to understanding tissue-specific regulation of gene expression, but current methods generally require large numbers of cells. This protocol describes two new low-input Capture-C approaches that can generate high-quality 3C interaction profi...

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Bibliographic Details
Main Authors: A. Marieke Oudelaar, Damien Downes, James Davies, Jim Hughes
Format: Article
Language:English
Published: Bio-protocol LLC 2017-12-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=2645&type=0