BEMSCA: A novel decision support tool applied to the optimal design of a large-scale human induced pluripotent stem cell expansion bioprocess

BEMSCA: A novel decision support tool applied to the optimal design of a large-scale human induced pluripotent stem cell expansion bioprocess

Human induced pluripotent stem cells (hiPSCs) are set to play a predominant role in the up-and-coming field of cell and gene therapy. However, if this is to become reality, hiPSCs must be made available in sufficiently large numbers, usually in the magnitude of billions of cells per patient. This ca...

Full description

Bibliographic Details
Main Authors: William O.S. Salvador, Diogo E.S. Nogueira, Frederico Castelo Ferreira, Joaquim M.S. Cabral, Carlos A.V. Rodrigues
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Biotechnology
Subjects:
Bioprocess economic modeling
Human induced pluripotent stem cells
Vertical-wheel bioreactors
Dextran sulfate supplementation
Low-density inoculation
B8 culture medium
Online Access:http://www.sciencedirect.com/science/article/pii/S259026282300045X

Internet

http://www.sciencedirect.com/science/article/pii/S259026282300045X

Similar Items