Hippocampal differential expression underlying the neuroprotective effect of delta-9-tetrahydrocannabinol microdose on old mice

Hippocampal differential expression underlying the neuroprotective effect of delta-9-tetrahydrocannabinol microdose on old mice

Delta-9-tetrahydrocannabinol (THC) is the primary psychoactive compound of the cannabis plant and an exogenous ligand of the endocannabinoid system. In previous studies, we demonstrated that a single microdose of THC (0.002 mg/kg, 3–4 orders of magnitude lower than the standard dose for rodents) exe...

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Bibliographic Details
Main Authors: Guy Shapira, Ifat Israel-Elgali, Meitar Grad, Eden Avnat, Lital Rachmany, Yosef Sarne, Noam Shomron
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Neuroscience
Subjects:
aging
tetrahydrocannabinol
neurodegenerative diseases
neuroprotection
endocannabinoid system
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1182932/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1182932/full

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