Sex-dependent effects of microglial reduction on impaired fear extinction induced by single prolonged stress

Sex-dependent effects of microglial reduction on impaired fear extinction induced by single prolonged stress

Single prolonged stress (SPS) is a preclinical rodent model for studying post-traumatic stress disorder (PTSD)-like behaviors. Previously we found that increased expression of the microglial marker Iba-1 in the ventral hippocampus after SPS exposure was associated with impaired fear extinction, sugg...

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Bibliographic Details
Main Authors: Orlando Torres-Rodriguez, Emily Ortiz-Nazario, Yesenia Rivera-Escobales, Bethzaly Velazquez, María Colón, James T. Porter
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
ventral hippocampus
fear extinction
microglia
cytokines
PTSD-like
sex-dependent
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1014767/full

Internet

https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1014767/full

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