The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy

The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy

Abstract Background Dimethylarginine dimethylaminohydrolase (DDAH) 1 maintains the bioavailability of nitric oxide by degrading asymmetric dimethylarginine (ADMA). Here, we aimed to investigate the effect of haptoglobin (Hp) genotype on the association of ADMA and DDAH 1 polymorphism with diabetic m...

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Bibliographic Details
Main Authors: Shiyun Wang, Zixuan Deng, Hong Zhang, Rong Zhang, Dandan Yan, Xiaojiao Zheng, Weiping Jia, Cheng Hu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cardiovascular Diabetology
Subjects:
Haptoglobin
Dimethylarginine dimethylaminohydrolase
Asymmetric dimethylarginine
Single nucleotide polymorphism
Diabetic macroangiopathy
Online Access:https://doi.org/10.1186/s12933-022-01702-6

Internet

https://doi.org/10.1186/s12933-022-01702-6

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