Upregulation of ATP6V0D2 benefits intracellular survival of Leishmania donovani in erythrocytes-engulfing macrophages

Upregulation of ATP6V0D2 benefits intracellular survival of Leishmania donovani in erythrocytes-engulfing macrophages

Visceral leishmaniasis (VL) is the most severe type of leishmaniasis which is caused by infection of Leishmania donovani complex. In the BALB/c mouse model of VL, multinucleated giant cells (MGCs) with heavy parasite infection consist of the largest population of hemophagocytes in the spleen of L. d...

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Bibliographic Details
Main Authors: Jing Hong, Budhaditya Mukherjee, Chizu Sanjoba, Junya Yamagishi, Yasuyuki Goto
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Leishmania
macrophage
multinucleated giant cell (MGC)
ATP6V0D2
iron
hemophagocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1332381/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1332381/full

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