MiR-210 promotes bone formation in ovariectomized rats by regulating osteogenic/adipogenic differentiation of bone marrow mesenchymal stem cells through downregulation of EPHA2

Abstract Purpose In osteoporosis, the balance between osteogenic and adipogenic differentiation of mesenchymal stem cells (MSCs) is disrupted. The osteogenic differentiation of bone marrow MSCs (BMSCs) is important for improving osteoporosis. The aim of this study was to explore the role and molecul...

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Bibliographic Details
Main Authors: Lijue Ren, Xiaohui Zhu, Jiuting Tan, Xiangyu Lv, Jiahui Wang, Fei Hua
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-023-04213-6