Clemastine Induces an Impairment in Developmental Myelination

Clemastine Induces an Impairment in Developmental Myelination

Abnormalities in myelination are associated to behavioral and cognitive dysfunction in neurodevelopmental psychiatric disorders. Thus, therapies to promote or accelerate myelination could potentially ameliorate symptoms in autism. Clemastine, a histamine H1 antagonist with anticholinergic properties...

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Bibliographic Details
Main Authors: Ana Palma, Juan Carlos Chara, Alejandro Montilla, Amaia Otxoa-de-Amezaga, Francisca Ruíz-Jaén, Anna M. Planas, Carlos Matute, Alberto Pérez-Samartín, María Domercq
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
clemastine
myelin
oligodendrocyte
microglia
development
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.841548/full

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https://www.frontiersin.org/articles/10.3389/fcell.2022.841548/full

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