Microfluidic thrombosis under multiple shear rates and antiplatelet therapy doses.

The mainstay of treatment for thrombosis, the formation of occlusive platelet aggregates that often lead to heart attack and stroke, is antiplatelet therapy. Antiplatelet therapy dosing and resistance are poorly understood, leading to potential incorrect and ineffective dosing. Shear rate is also su...

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Bibliographic Details
Main Authors: Melissa Li, Nathan A Hotaling, David N Ku, Craig R Forest
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3880267?pdf=render