Cytotoxic, analgesic and anti-inflammatory activity of colchicine and its C-10 sulfur containing derivatives

Abstract 10-Alkylthiocolchicines have been obtained and characterized by spectroscopic methods and their biological activities as: cytotoxic, anti-inflammatory and analgesic activities have been tested. Cytotoxic activity against SKOV-3 ovarian cell line for 10-alkylthiocolchicine analogues was repo...

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Bibliographic Details
Main Authors: Joanna Kurek, Krzysztof Myszkowski, Irena Okulicz-Kozaryn, Agnieszka Kurant, Ewa Kamińska, Michał Szulc, Błażej Rubiś, Mariusz Kaczmarek, Przemysław Ł. Mikołajczak, Marek Murias
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88260-1