Design and synthesis of novel substituted pyrazole as small molecule inhibitor of cytochrome P450 CYP121A1

Discovering new drugs with novel targets is vital for the success of treatment of tuberculosis as antibiotic resistance is increasing among the TB population. Mycobacterium tuberculosis cytochrome P450 CYP121A1 is a promising drug target for the treatment of tuberculosis owing to its essential role...

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Bibliographic Details
Main Authors: Mitali Jasani, Laxman Patel
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622004581