Mechanism of MRX inhibition by Rif2 at telomeres

Different proteins localised at telomeres ensure chromosome end stability to prevent double strand-end break recognition. Here the authors provide new insight into how in S. cerevisiae the interaction between Rif2 and Rad50 inhibits MRX functions at telomeres.

Bibliographic Details
Main Authors: Florian Roisné-Hamelin, Sabrina Pobiega, Kévin Jézéquel, Simona Miron, Jordane Dépagne, Xavier Veaute, Didier Busso, Marie-Hélène Le Du, Isabelle Callebaut, Jean-Baptiste Charbonnier, Philippe Cuniasse, Sophie Zinn-Justin, Stéphane Marcand
Format: Article
Language:English
Published: Nature Portfolio 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23035-w