Exploring the Effectiveness of Acyclovir against Ranaviral Thymidine Kinases: Molecular Docking and Experimental Validation in a Fish Cell Line

Exploring the Effectiveness of Acyclovir against Ranaviral Thymidine Kinases: Molecular Docking and Experimental Validation in a Fish Cell Line

The effectiveness of acyclovir, a selective anti-herpesvirus agent, was tested both in silico and in vitro against two ranaviruses, namely the European catfish virus (ECV) and Frog virus 3 (FV3). ECV can cause significant losses in catfish aquaculture, while FV3 poses a risk to vulnerable amphibian...

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Bibliographic Details
Main Authors: Richárd Rácz, Ákos Gellért, Tibor Papp, Andor Doszpoly
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Life
Subjects:
acyclovir
molecular docking
antiviral effect
European catfish virus
Frog virus 3
Ictalurid herpesvirus 2
Online Access:https://www.mdpi.com/2075-1729/14/9/1050

Internet

https://www.mdpi.com/2075-1729/14/9/1050

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