The expression of IGFBP-5 in the reproductive axis and effect on the onset of puberty in female rats

The expression of IGFBP-5 in the reproductive axis and effect on the onset of puberty in female rats

Abstract Insulin-like growth factor-binding protein-5 (IGFBP-5) has recently been shown to alter the reproductive capacity by regulating insulin-like growth factor (IGF) bioavailability or IGF-independent effects. The present study aimed to investigate the effect and mechanism of IGFBP-5 on the onse...

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Bibliographic Details
Main Authors: Zhiqiu Yao, Maosen Lin, Tao Lin, Xinbao Gong, Pin Qin, Hailing Li, Tiezhu Kang, Jing Ye, Yanyun Zhu, Qiwen Hong, Ya Liu, Yunsheng Li, Juhua Wang, Fugui Fang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
Insulin-like growth factor-binding protein-5 (IGFBP-5)
Hypothalamus
Reproductive axis
Rat
Puberty
Online Access:https://doi.org/10.1186/s12958-022-00966-7

Internet

https://doi.org/10.1186/s12958-022-00966-7

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