A chemokine network of T cell exhaustion and metabolic reprogramming in renal cell carcinoma

A chemokine network of T cell exhaustion and metabolic reprogramming in renal cell carcinoma

Renal cell carcinoma (RCC) is frequently infiltrated by immune cells, a process which is governed by chemokines. CD8+ T cells in the RCC tumor microenvironment (TME) may be exhausted which most likely influence therapy response and survival. The aim of this study was to evaluate chemokine-driven T c...

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Bibliographic Details
Main Authors: Renate Pichler, Peter J. Siska, Piotr Tymoszuk, Agnieszka Martowicz, Gerold Untergasser, Roman Mayr, Florian Weber, Andreas Seeber, Florian Kocher, Dominik A. Barth, Martin Pichler, Martin Thurnher
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
RCC
chemokines
immunotherapy
metabolism
OXPHOS
T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1095195/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1095195/full

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