Galectins induced from hemocytes bridge phosphatidylserine and N-glycosylated Drpr/CED-1 receptor during dendrite pruning

Galectins induced from hemocytes bridge phosphatidylserine and N-glycosylated Drpr/CED-1 receptor during dendrite pruning

Abstract During neuronal pruning, phagocytes engulf shed cellular debris to avoid inflammation and maintain tissue homeostasis. How phagocytic receptors recognize degenerating neurites had been unclear. Here, we identify two glucosyltransferases Alg8 and Alg10 of the N-glycosylation pathway required...

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Bibliographic Details
Main Authors: Hsin-Ho Sung, Hsun Li, Yi-Chun Huang, Chun-Lu Ai, Ming-Yen Hsieh, Hau-Ming Jan, Yu-Ju Peng, Hsien-Ya Lin, Chih-Hsuan Yeh, Shu-Yu Lin, Chun-Yen Yeh, Ying-Ju Cheng, Kay-Hooi Khoo, Chun-Hung Lin, Cheng-Ting Chien
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-51581-6

Internet

https://doi.org/10.1038/s41467-024-51581-6

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