Transmembrane adaptor proteins in the high-affinity IgE receptor signaling

Transmembrane adaptor proteins in the high-affinity IgE receptor signaling

Aggregation of the high-affinity IgE receptor (FcεRI) initiates a cascade of signaling events leading to release of preformed inflammatory and allergy mediators and de novo synthesis and secretion of cytokines and other compounds. The first biochemically well defined step of this signaling cascade i...

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Bibliographic Details
Main Authors: Petr eDraber, Ivana eHalova, Francesca eLevi-Schaffer, Lubica eDraberova
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Immunology
Subjects:
mast cell
IgE receptor
plasma membrane
Transmembrane adaptor proteins
LAT/LAT1
LAX
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00095/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00095/full

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