The epithelial Na+ channel UNC-8 promotes an endocytic mechanism that recycles presynaptic components to new boutons in remodeling neurons

Summary: Circuit refinement involves the formation of new presynaptic boutons as others are dismantled. Nascent presynaptic sites can incorporate material from recently eliminated synapses, but the recycling mechanisms remain elusive. In early-stage C. elegans larvae, the presynaptic boutons of GABA...

Full description

Bibliographic Details
Main Authors: Andrea Cuentas-Condori, Siqi Chen, Mia Krout, Kristin L. Gallik, John Tipps, Casey Gailey, Leah Flautt, Hongkyun Kim, Ben Mulcahy, Mei Zhen, Janet E. Richmond, David M. Miller, III
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723013396