The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin

The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin

ABSTRACT Legionella pneumophila is a bacterial pathogen ubiquitous in natural and man-made aquatic environments, where it replicates in protozoa. Its intracellular life cycle depends on the establishment of a Legionella-containing vacuole (LCV) where the bacteria replicate. To form the LCV, L. pneum...

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Bibliographic Details
Main Authors: Monica Rolando, Ivy Yeuk Wah Chung, Caishuang Xu, Laura Gomez-Valero, Patrick England, Miroslaw Cygler, Carmen Buchrieser
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Legionella pneumophila
host-pathogen interactions
histone methyltransferase
epigenetics
H3K14
Online Access:https://journals.asm.org/doi/10.1128/mbio.01655-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01655-23

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