Molecular characterization of sub-frontal recurrent medulloblastomas reveals potential clinical relevance

Molecular characterization of sub-frontal recurrent medulloblastomas reveals potential clinical relevance

BackgroundSingle recurrence in the sub-frontal region after cerebellar medulloblastoma (MB) resection is rare and the underlying molecular characteristics have not been specifically addressed.MethodsWe summarized two such cases in our center. All five samples were molecularly profiled for their geno...

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Bibliographic Details
Main Authors: Zirong Chen, Huaitao Yang, Jiajia Wang, Guoxian Long, Qingsong Xi, Tao Chen, Yue He, Bin Zhang, Feng Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Neurology
Subjects:
medulloblastoma
postoperative recurrence
radiation dose
whole genome sequencing
RNA-sequencing
DNA methylation
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1148848/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2023.1148848/full

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