Secretory IgA impacts the microbiota density in the human nose

Secretory IgA impacts the microbiota density in the human nose

Abstract Background Respiratory mucosal host defense relies on the production of secretory IgA (sIgA) antibodies, but we currently lack a fundamental understanding of how sIgA is induced by contact with microbes and how such immune responses may vary between humans. Defense of the nasal mucosal barr...

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Bibliographic Details
Main Authors: Rob van Dalen, Ahmed M. A. Elsherbini, Mareike Harms, Svenja Alber, Regine Stemmler, Andreas Peschel
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Microbiome
Subjects:
Mucosal immunology
Secretory IgA
IgA-seq
Nasal antibodies
Nasal microbiota
Online Access:https://doi.org/10.1186/s40168-023-01675-y

Internet

https://doi.org/10.1186/s40168-023-01675-y

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