Gender specific factors contributing to cognitive resilience in APOE ɛ4 positive older adults in a population-based sample

Abstract Although APOE ɛ4 has been identified as the strongest genetic risk factor for Alzheimer’s Disease, there are some APOE ɛ4 carriers who do not go on to develop Alzheimer’s disease or cognitive impairment. This study aims to investigate factors contributing to this “resilience” separately by...

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Bibliographic Details
Main Authors: Lidan Zheng, Ranmalee Eramudugolla, Nicolas Cherbuin, Shannon M. Drouin, Roger A. Dixon, Kaarin J. Anstey
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34485-1