Protective Effect of Zinc Against Ischemic Neuronal Injury in a Middle Cerebral Artery Occlusion Model

Protective Effect of Zinc Against Ischemic Neuronal Injury in a Middle Cerebral Artery Occlusion Model

Abstract.: In this study, we investigated the effect of vesicular zinc on ischemic neuronal injury. In cultured neurons, addition of a low concentration (under 100 µM) of zinc inhibited both glutamate-induced calcium influx and neuronal death. In contrast, a higher concentration (over 150 µM) of zin...

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Bibliographic Details
Main Authors: Youji Kitamura, Yasuhiko Iida, Jun Abe, Masashi Ueda, Masaki Mifune, Fumiyo Kasuya, Masayuki Ohta, Kazuo Igarashi, Yutaka Saito, Hideo Saji
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319345268

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http://www.sciencedirect.com/science/article/pii/S1347861319345268

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