Metformin treatment of juvenile mice potentiates innate immune response to bacterial lipopolysaccharide in males

Objective: Metformin is a widely used drug, with a good safety profile, for treatment of type 2 diabetes. Recently, it has been found to also exhibit immunomodulatory potential. We aim to preliminarily explore the potential role of metformin in regulating innate immunity using UM-HET3 mice. Methods:...

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Bibliographic Details
Main Authors: Yujie Sun, Yun Zhu, Andrzej Bartke, Lin Lin, Rong Yuan
Format: Article
Language:English
Published: SAGE Publishing 2023-08-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X231199369