Exosome-derived tRNA fragments tRF-GluCTC-0005 promotes pancreatic cancer liver metastasis by activating hepatic stellate cells

Exosome-derived tRNA fragments tRF-GluCTC-0005 promotes pancreatic cancer liver metastasis by activating hepatic stellate cells

Abstract Early metastasis is the primary factor in the very poor prognosis of pancreatic ductal adenocarcinoma (PDAC), with liver metastasis being the most common form of distant metastasis in PDAC. To investigate the mechanism of PDAC liver metastasis, we found that PDAC cells can promote the forma...

Full description

Bibliographic Details
Main Authors: Wei Chen, Wang Peng, Ronghua Wang, Shuya Bai, Mengdie Cao, Si Xiong, Yanling Li, Yilei Yang, Jingwen Liang, Luyao Liu, Hamza O. Yazdani, Yuchong Zhao, Bin Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-06482-3

Internet

https://doi.org/10.1038/s41419-024-06482-3

Similar Items