Bioengineered tissue and cell therapy products are efficiently cryopreserved with pathogen-inactivated human platelet lysate-based solutions

Abstract Background There remains much interest in improving cryopreservation techniques for advanced therapy medicinal products (ATMPs). Recently, human platelet lysate (hPL) has emerged as a promising candidate to replace fetal bovine serum (FBS) as a xeno-free culture supplement for the expansion...

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Main Authors: María Martín-López, Cristina Rosell-Valle, Blanca Arribas-Arribas, Beatriz Fernández-Muñoz, Rosario Jiménez, Sonia Nogueras, Ana Belén García-Delgado, Fernando Campos, Mónica Santos-González
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-023-03300-z