Design and synthesis of doublecortin-like kinase 1 inhibitors and their bioactivity evaluation

AbstractDoublecortin-like kinase 1 (DCLK) is a microtubule-associated serine/threonine kinase that is upregulated in a wide range of cancers and is believed to be related to tumour growth and development. Upregulated DCLK1 has been used to identify patients at high risk of cancer progression and tum...

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Bibliographic Details
Main Authors: Pengming Pan, Dengbo Ji, Zhongjun Li, Xiangbao Meng
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/14756366.2023.2287990