| Summary: | Several products have been developed to eliminate or
reduce potential pathogenic microorganisms of the
oral microbiome. The continuous use of these synthetic
products can result in side effects such as vomiting,
diarrhea, darkening of the teeth and the induction of
microbial resistance. Pomegranate (Punica granatum)
peel decoction was tested to assess its antimicrobial
activity. In vitro analysis showed the decoction had
antimicrobial activity against strains of Pseudomonas
aeruginosa and Candida albicans, but none was
detected against Enterococcus faecalis. When tested
on saliva samples from children, the decoction showed
great potential in reducing the load of microorganisms,
the inhibition haloes produced with saliva samples
being similar to those of the antimicrobial control
(0.12% chlorhexidine). The pomegranate peel decoction
in water could thus provide a promising source for
developing solutions for use against oral diseases.
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