Store-Operated Calcium Entry Contributes to Cisplatin-Induced Cell Death in Non-Small Cell Lung Carcinoma

Store-Operated Calcium Entry Contributes to Cisplatin-Induced Cell Death in Non-Small Cell Lung Carcinoma

Cisplatin (CDDP) is one of the principal chemotherapeutic agents used for the first-line treatment of many malignancies, including non-small cell lung carcinoma (NSCLC). Despite its use for over 40 years, its mechanism of action is not yet fully understood. Store-operated calcium entry (SOCE), the m...

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Bibliographic Details
Main Authors: Roberta Gualdani, Marie de Clippele, Ikram Ratbi, Philippe Gailly, Nicolas Tajeddine
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
store-operated calcium entry
cisplatin
apoptosis
reactive oxygen species
mitochondrial calcium
non-small cell lung carcinoma
Online Access:https://www.mdpi.com/2072-6694/11/3/430

Internet

https://www.mdpi.com/2072-6694/11/3/430

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