Bistability in a metabolic network underpins the de novo evolution of colony switching in Pseudomonas fluorescens.

Phenotype switching is commonly observed in nature. This prevalence has allowed the elucidation of a number of underlying molecular mechanisms. However, little is known about how phenotypic switches arise and function in their early evolutionary stages. The first opportunity to provide empirical ins...

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Bibliographic Details
Main Authors: Jenna Gallie, Eric Libby, Frederic Bertels, Philippe Remigi, Christian B Jendresen, Gayle C Ferguson, Nicolas Desprat, Marieke F Buffing, Uwe Sauer, Hubertus J E Beaumont, Jan Martinussen, Mogens Kilstrup, Paul B Rainey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4357382?pdf=render