Drug-loaded oleic-acid grafted mesoporous silica nanoparticles conjugated with α-lactalbumin resembling BAMLET-like anticancer agent with improved biocompatibility and therapeutic efficacy

Drug-loaded oleic-acid grafted mesoporous silica nanoparticles conjugated with α-lactalbumin resembling BAMLET-like anticancer agent with improved biocompatibility and therapeutic efficacy

Despite its prominent therapeutic efficacy, chemotherapy has raised serious concerns due to the severe adverse effects and multidrug resistance evoked, which propels the search for safe and green therapeutic agents. BAMLET (bovine α-lactalbumin made lethal against tumor cell) is a well-known protein...

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Bibliographic Details
Main Authors: Wei Pei, Ling Cai, Xing Gong, Li Zhang, Jiarong Zhang, Ping Zhu, Huijun Jiang, Chao Wang, Shoulin Wang, Jin Chen
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Materials Today Bio
Subjects:
Drug delivery
Mesoporous silica nanoparticle
BAMLET
α-lactalbumin
Protein corona
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422000709

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http://www.sciencedirect.com/science/article/pii/S2590006422000709

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