Immunogenicity and Tolerability of a SARS-CoV-2 TNX-1800, a Live Recombinant Poxvirus Vaccine Candidate, in Syrian Hamsters and New Zealand White Rabbits

TNX-1800 is a preclinical stage synthetic-derived live attenuated chimeric horsepox virus vaccine engineered to express the SARS-CoV-2 spike (S) gene. The objectives of this study were to assess the safety, tolerability, and immunogenicity of TNX-1800 administration in Syrian golden hamsters and New...

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Bibliographic Details
Main Authors: Mayanka Awasthi, Anthony Macaluso, Scott J. Goebel, Erin Luea, Ryan S. Noyce, Farooq Nasar, Bruce Daugherty, Sina Bavari, Seth Lederman
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/10/2131