Mechanisms of Epithelial-Mesenchymal Transition and Prevention of Dispase-Induced PVR by Delivery of an Antioxidant αB Crystallin Peptide

Mechanisms of Epithelial-Mesenchymal Transition and Prevention of Dispase-Induced PVR by Delivery of an Antioxidant αB Crystallin Peptide

Proliferative Vitreoretinopathy (PVR) is a refractory retinal disease whose primary pathogenesis involves the epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells. At present, there is no effective treatment other than surgery for PVR. The purpose of this study was to in...

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Bibliographic Details
Main Authors: Iori Wada, Parameswaran G Sreekumar, Christine Spee, Andrew J MacKay, Michael Ip, Ram Kannan
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antioxidants
Subjects:
PVR
retinal pigment epithelium
EMT
MET
ROS
mitochondrial function
Online Access:https://www.mdpi.com/2076-3921/11/10/2080

Internet

https://www.mdpi.com/2076-3921/11/10/2080

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