The identification of CD163 expressing phagocytic chondrocytes in joint cartilage and its novel scavenger role in cartilage degradation.

BACKGROUND: Cartilage degradation is a typical characteristic of arthritis. This study examined whether there was a subset of phagocytic chondrocytes that expressed the specific macrophage marker, CD163, and investigated their role in cartilage degradation. METHODS: Cartilage from the knee and tempo...

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Main Authors: Kai Jiao, Jing Zhang, Mian Zhang, Yuying Wei, Yaoping Wu, Zhong Ying Qiu, Jianjun He, Yunxin Cao, Jintao Hu, Han Zhu, Li-Na Niu, Xu Cao, Kun Yang, Mei-Qing Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3543453?pdf=render