Characterization of Pathway-Specific Regulator NigR for High Yield Production of Nigericin in <i>Streptomyces malaysiensis</i> F913
Nigericin is a polyether antibiotic with potent antibacterial, antifungal, antimalarial and anticancer activity. NigR, the only regulator in the nigericin biosynthetic gene cluster in <i>Streptomyces malaysiensis</i> F913, was identified as a SARP family regulator. Disruption of <i>...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
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| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/11/7/938 |