Modification of Intestinal Microbiota Dysbiosis by Low-Dose Interleukin-2 in Dermatomyositis: A Post Hoc Analysis From a Clinical Trial Study

Modification of Intestinal Microbiota Dysbiosis by Low-Dose Interleukin-2 in Dermatomyositis: A Post Hoc Analysis From a Clinical Trial Study

The microbiota has been observed altered in autoimmune diseases, including idiopathic inflammatory myopathies (IIMs), and associated with different treatments. Low-dose IL-2 treatment emerges as a new option for active IIMs. This study aims to explore the role of low-dose IL-2 in regulating intestin...

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Bibliographic Details
Main Authors: Yunzhi Zhufeng, Jun Xu, Miao Miao, Yifan Wang, Yimin Li, Bo Huang, Yixue Guo, Jiayi Tian, Xiaolin Sun, Jing Li, Dan Lu, Zhanguo Li, Yuhui Li, Jing He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
gut microbiota
idiopathic inflammatory myopathies
low-dose IL-2
Tregs
NOD mice
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.757099/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.757099/full

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