EZH2 serves as a viable therapeutic target for myeloma-induced osteolytic bone destruction

Abstract Myelomatous bone disease is a complication characterized by lytic bone lesions, reduced bone formation, bone pain, and increased fracture risk. Understanding these underlying mechanisms is crucial for developing effective therapeutic approaches. Here we show the role of enhancer of zeste ho...

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Bibliographic Details
Main Authors: Rui Liu, Zongwei Li, Rui Chen, Zhihong Fang, Zhiqiang Liu, Huan Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56506-5