Revisiting the Checkerboard to Inform Development of β-Lactam/β-Lactamase Inhibitor Combinations

A two-dimensional “checkerboard” array employing systematic titration (e.g., serial two-fold dilutions) is a well-established in vitro method for exploring the antibacterial effects of novel drug combinations. Minimum inhibitory concentrations (MICs) on the checkerboard are isoeffective points at wh...

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Bibliográfalaš dieđut
Váldodahkki: Darren J. Bentley
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: MDPI AG 2024-04-01
Ráidu:Antibiotics
Fáttát:
Liŋkkat:https://www.mdpi.com/2079-6382/13/4/337