Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics

Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics

Glioblastoma is the most common and aggressive brain tumor, associated with poor prognosis and survival, representing a challenging medical issue for neurooncologists. Dysregulation of histone-modifying enzymes (HDACs) is commonly identified in many tumors and has been linked to cancer proliferation...

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Bibliographic Details
Main Authors: Lorenzo Taiarol, Chiara Bigogno, Silvia Sesana, Marcelo Kravicz, Francesca Viale, Eleonora Pozzi, Laura Monza, Valentina Alda Carozzi, Cristina Meregalli, Silvia Valtorta, Rosa Maria Moresco, Marcus Koch, Federica Barbugian, Laura Russo, Giulio Dondio, Christian Steinkühler, Francesca Re
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
glioblastoma
liposomes
HDAC inhibitor
brain
cancer
Online Access:https://www.mdpi.com/2072-6694/14/12/2978

Internet

https://www.mdpi.com/2072-6694/14/12/2978

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