Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages.

Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages.

Autism is a highly heritable neurodevelopmental disorder, yet the genetic underpinnings of the disorder are largely unknown. Aberrant brain overgrowth is a well-replicated observation in the autism literature; but association, linkage, and expression studies have not identified genetic factors that...

Full description

Bibliographic Details
Main Authors: Maggie L Chow, Tiziano Pramparo, Mary E Winn, Cynthia Carter Barnes, Hai-Ri Li, Lauren Weiss, Jian-Bing Fan, Sarah Murray, Craig April, Haim Belinson, Xiang-Dong Fu, Anthony Wynshaw-Boris, Nicholas J Schork, Eric Courchesne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3310790?pdf=render

Internet

http://europepmc.org/articles/PMC3310790?pdf=render

Similar Items