Rapid functional analysis of computationally complex rare human IRF6 gene variants using a novel zebrafish model.
Large-scale sequencing efforts have captured a rapidly growing catalogue of genetic variations. However, the accurate establishment of gene variant pathogenicity remains a central challenge in translating personal genomics information to clinical decisions. Interferon Regulatory Factor 6 (IRF6) gene...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-09-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC5628943?pdf=render |